South Carolina Car Rentals

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Prices are based on searches made during the previous 7 days. Price is dynamic and varies based on the date of the booking, length of rental and car class.
There is no guarantee this price will be in effect at the time of your search.

Car Rental in South Carolina: What you need to know

Get a taste of true Southern hospitality the next time you travel to South Carolina. Located in the lower portion of the United States, the Palmetto State is home to stunning coastlines and lush forests. Discover everything from Myrtle Beach to the Francis Marion National Forest with rental cars in South Carolina. Let the adventure begin in Greenville, where performances at the Peace Center for the Performing Arts and the stunning Falls Park on the Reedy await you. Then travel southeast to Columbia, the state capital, where you can shop ‘til your drop at Five Points and go wild at the Riverbanks Zoo.

Once you’re ready to continue your road trip, make your way to Charleston and spend a peaceful day at the Magnolia Plantation and Gardens before getting your feet sandy at the Isle of Palms. Finish up your journey in Hilton Head by putting around on the golf course and viewing the Harbour Town Lighthouse. With a South Carolina car rental, the state is yours for the taking.

Popular Destinations in South Carolina
Rent a car in Myrtle Beach and work on your tan at the Boardwalk.
Drive to tour the lighthouses of Hilton Head.

How can I get a cheap car rental in South Carolina?

Here's our recommendations on how to hit the road with extra cash in your pocket:

  • Use our convenient filter feature to point you in the direction of the hottest car deals in town and and then compare the prices;
  • Check your inbox for our awesome Price Drop Alert. We'll give you the intel on all the great deals cruising around your location;
  • Look at the offers at all rental locations, including the airport terminal and its vicinity. A short cab trip to a close-by rental car office may mean significant savings;
  • You can sometimes save a pretty penny if your plans are flexible. Play with different days and dates and see how much you can save;
  • No one likes being charged a late fee. Avoid the stress of having to pay for another full day by ensuring your pickup and drop-off times are at similar times;
  • Keep more hard-earned dollars in your purse. You'll get some of the cheapest deals when you pay in advance for your vehicle;
  • Book as soon as your dates are set. You'll get the biggest selection early on.
Enterprise car rental locations in South Carolina
39 locations
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National car rental locations in South Carolina
5 locations
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Hertz car rental locations in South Carolina
21 locations
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Budget car rental locations in South Carolina
12 locations
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Avis car rental locations in South Carolina
9 locations
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Alamo car rental locations in South Carolina
5 locations
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Thrifty car rental locations in South Carolina
6 locations
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Dollar car rental locations in South Carolina
5 locations
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Car Rentals in Top Destinations