Take your rental wheels downtown to Main Street to check out the revitalized central hub. The constant influx of university students means you’ll find no end to the bars, restaurants, and cafes that have sprung up to facilitate studying and socializing. Many of the buildings downtown were built between the 1860s and 1930s, and reflect the changing architectural styles of their eras. For a special (and delicious) trip into history, drive your Statesboro car rental about 12 miles south to Meinhardt Vineyards & Winery. Billed as Southeast Georgia’s first winery, you can attend a tasting of the delicious local wines or enjoy dinner.